Ketamine Treatment Plan

Intravenous Ketamine

IV ketamine infusions have emerged as the standard among Ketamine providers, even with the introduction of the nasal spray Spravato. Patients seeking treatment for mood disorders typically receive a series of 6 infusions, known as the loading phase, completed over a 2 week period. Each infusion lasts 45-55 minutes. There are no known long-term side effects, and the short-term side effects are usually mild and do not last more than a day.  Clinical studies have consistently shown a 70% success rate with this approach.

Like with all chronic illness, maintenance therapy is required to sustain the effect and keep symptoms managed. Booster infusions, which are the same duration as the loading phase infusions, are single infusions on an as-needed basis in this maintenance phase. For pain syndromes, patients typically receive anywhere from 3-7 infusions lasting 4 hours over the course of a few weeks. Again, these treatments require boosters as time goes on.

The time between boosters varies for each patient and is determined by the number of initial infusions during the loading phase and the percentage of pain that returns over time in each patient. We have been utilizing this treatment protocol since we opened Midwest Ketamine Center in 2016 and our protocol has a success rate that is consistent with clinical studies. It is superior to both intramuscular shots as well as intranasal sprays.

Ketamine therapy for mood disorders and pain syndromes is off-label, meaning it lacks FDA approval. It is safe OFF-LABEL use of this medication as we administer it under a controlled setting with a physician monitoring you.

Since the use of Ketamine is OFF-LABEL insurance companies or Medicaid/Medicare will NOT COVER its use for treating depression. We can only accept cash or credit cards as payment. We cannot accept checks of any kind.



On the day of each infusion, you will need someone to accompany you to your appointment and drive you home as the Ketamine will leave you a little tired.
  • Please wear comfortable loose clothing so we are able to easily place the cardiac monitor leads under your shirt.
  • Bring a light blanket of your choice.
  • You may bring headphones and listen to the music of your choosing, preferably something soothing to you.
Infusion times vary depending on the disease we are treating. We will pretreat you with nausea medication when you first arrive at the center as Ketamine can cause some nausea in a minority of patients.  You can still eat and drink as you normally would the day of your treatment. Most people find the Ketamine infusion experience to be pleasant.  Infusions are given in private rooms. Patients do not usually sleep as the dose given is lower than an anesthetic dose. The infusion for mood disorders generally lasts about 45 minutes, while for pain disorders, can be several hours. Most effects of the medicine wear off within minutes after the infusion, but patients can feel more tired than usual for a few hours after the infusion. Ketamine is generally well-tolerated, but if any side effects are encountered such as visual disturbances or elevated blood pressure, our staff will quickly give IV medications to counteract them. After infusions are completed, the duration of symptom relief can be variable.  Most patients will feel well for 1-2 months, but some can respond for up to 6 months.  Single booster infusions can be scheduled to achieve symptom relief again, and generally, no more is needed than a single booster infusion to achieve a similar length of symptom relief.

Ketamine infusions typically are not covered by insurance carriers. Treatments are considered an out-of-pocket expense. We will provide you with our billing sheets so you can submit them to your insurance company, but we do not directly do preauthorizations with insurance companies.

Mood Disorder Treatments usually consist of a series of 6 treatments over a 2 week period. Each IV infusion lasts approximately one hour.

$500 per infusion for Mood Disorders.

Chronic Pain Disorder Treatments usually consist of a series of at least 3 treatments depending on the type of pain syndrome you have, but may require 7-10 total sessions. These are generally 4-hour infusion sessions.

$1250 per treatment for Chronic Pain.

Infusion cost includes every aspect of treatment, with no added costs.

We accept all major credit cards and cash. No checks accepted.

Click here to apply for interest-free financing via Advance Care.

Contact us to determine an appropriate treatment plan and determine if you are a good candidate for Ketamine.

If you have suffered from Mood Disorders:
  • Major depression
  • PTSD
  • OCD
  • Anxiety
  • Bipolar disorders

If you have suffered from Chronic Pain Syndromes:

  • Trigeminal neuralgia
  • TMJ syndrome
  • Neuropathic pain
  • Chronic back/Musculoskeletal pain
And have been refractory to standard therapies you may be a good Ketamine Treatment candidate. If you have been under a physician’s care and already tried recommended medical therapies but are not feeling better, you may be considered for Ketamine Treatment. You must be under the care of a psychiatrist, primary physician, or pain specialist to be considered for treatment. Patients that are on MAO-I type medications such as Isocarboxazid (Marplan), Phenelzine (Nardil), Selegiline (Emsam), or Tranylcypromine (Parnate), need to be tapered off their medication 2 weeks prior to infusions. Patients that are on high doses of benzodiazepines such as Alprazolam (Xanax), Lorazepan (Ativan), Clonazepam (Klonopin), or Diazepam (Valium) may consider decreasing to lower doses prior to infusion, but they may remain on these medications during the infusion time. We do not offer treatment to patients who have been diagnosed with schizophrenia or schizoaffective disorder. You are not a good candidate if you have an ongoing addiction to or misuse of drugs or alcohol. If you are pregnant, or breastfeeding you are not a good candidate for treatment. If you have uncontrolled hypertension, congestive heart failure, or cardiac disease, we must optimize your medical regimen prior to treatment. Please contact us with any questions about your eligibility.